The rate at which infertility is fast becoming a common phenomenon in today's hectic stressful lives, is rather alarming, all thanks to our current lifestyle taking a toll on our overall health. In humans, azoospermia affects about 1% of the male population and may be seen in up to 20% of male infertility situations. Azoospermia is defined as the complete lack of sperm in the ejaculate. If this is the case, then one or both of two conditions may be present.

  • There is a problem with sperm production.
  • There is a blockage such that sperm production, although normal, cannot reach the ejaculate.
How sperms develop :

When boy becomes of 14 years of age then L.H. & F.S.H. hormone secretion from pituitary increases. The rise in these hormones leads to proliferation of sperm forming cells (Germ Cells) in the testis. These germ cells start multiplying under the effect of above-mentioned pituitary hormones along with assistance of other hormones as testosterones, Growth hormones, Androstenidione, insulin like growth factor-I, Thyroids hormone, paracrine hormone & growth factors.


Under the control of above-mentioned hormones germs cells divide & transformed into primary spermatocytes. Then further maturation of primary spermatocytes to spermatids & then finally into mature spermatozoa (i.e. normal sperms) occurs under the control of above-mentioned hormones. After few weeks of progressive maturation inside the testis these sperms become normally motile & develop the capacity to fertilize the ovum. This total sperm cycle, from first stage to final stage of normal mature sperms is of three months. Thus to produce normal sperms testis should have normal sperm producing germ cells & normal regulating hormones. Any major hindrance in the development of these spermatozoa will lead to absent sperm production resulting into nil sperm.

What causes azoospermia?

Azoospermia may occur if the flow of sperm is blocked and cannot leave the body (obstructive cause). Azoospermia may also be caused by a problem with sperm production (nonobstructive cause).

Obstructive azoospermia :

  • Genetic conditions such as congenital bilateral absence of the vas deferens, may affect sperm transport
  • Infections of the male reproductive system, such as in the testicles or prostate, may affect male fertility.
  • Trauma may cause azoospermia. Previous injury or surgery to the spine, pelvis, lower abdomen, or male sex organs may cause damage to the male reproductive system. This may include surgery on an inguinal (groin) hernia. Trauma may affect sperm production or cause an obstruction in the flow or transport of sperm.
  • A varicocele is a condition that causes the veins (blood vessels) in the scrotum to become enlarged and dilated (widened).

Nonobstructive azoospermia :

  • Medicines such as steroids, antibiotics, and medicines used to treat inflammation or cancer may affect male fertility.
  • Smoking, drinking alcohol, and using illegal drugs may also cause problems with sperm production.
  • Genetic conditions may affect sperm production or development of reproductive organs. These include Klinefelter syndrome and Kallmann syndrome.
  • Abnormal hormone levels may be caused by disorders of the testicles. This may affect the production of sperm.
  • Radiation used to treat cancer may affect sperm production.
  • Retrograde ejaculation is a condition that causes semen to travel into the bladder instead of outside the body. It is usually caused by a problem with the neck of the bladder and may be due to spinal cord injuries, medicines, or diabetes.
  • Other causes include pesticides, heavy metals, heat, and undescended testes (testicles that did move from the abdomen into the scrotum). Any of these can affect sperm production.

What are the signs and symptoms of azoospermia?
  • Inability to get your partner pregnant
  • Increased body fat, body hair, and breast tissue
  • Clear, watery, or whitish discharge from the penis
  • Presence of a mass or swelling on the scrotum that feels like a bag of worms (varicocele)
  • Stress or emotional pressure from not being able to conceive a child
  • Testicles that are small, soft, or cannot be felt
  • Veins that are enlarged, twisted, and may be seen in the scrotum (varicocele)
Self-care :
  • Avoid chemicals : Chemicals, such as pesticides, may lower your sperm count.
  • Reduce alcohol intake : Alcohol decreases sperm production.
  • Do not smoke : If you smoke, it is never too late to quit. Nicotine may affect the condition of your semen.
  • Do not take hot baths or wear tight underwear : Heat decreases sperm production. Tight underwear, such as briefs, keeps testicles close to the body. This can increase their temperature and decrease sperm production.
  • Vitamins & Minerals : Minerals and vitamins are very important for normal functioning of your body, and some of them can really help you increase sperm count naturally. As a result, you must consume foods that are rich in vitamins B and C, zinc and chromium. In order to increase your daily intake of the mentioned substances, you can also take different supplements.
  • Stay in good shape : A good physical condition is often the key to avoiding fertility problems in men. By exercising regularly exercises, you not only stimulate the development of your muscular mass and the functioning of your internal organs, but you also maintain your weight under control. Many studies prove that men who are excessively thin or overweight have lower chances to become parents.

Ayurvedic treatment for Azoospermia

There is no satisfactory treatment of Azoospermia in allopathic treatment system hence ayurvedic treatment is most preferred treatment for this condition. The treatment involves both medicinal treatment as well as Panchkarma treatment for the same.

Medicinal Treatment :

Various herbs are known for their effects in increasing the sperm count of the patients eg. Safed Musli, Gokshr, Satavari, Ashwaganda, Shilajit, Kawach etc. Along with the herbs there are various classical combinations which are very helpful for treating this condition like Makardhwaj wati, Suwarna Siddha Makardhwaj, Shilajeetvadi wati, etc. Evidence of the use of herbal remedies for male infertility dates all the way back to 5000 BC. Here are some beneficial ayurvedic plants and remedies. Gokshur is one of the herbs that cure azoospermia. It is used for many years in fertility related problems, low male libido and other sexual disorders like erectile dysfunction. Gokshur increases the level of estrogen and testosterone and also improves the blood circulation in the entire area, but mainly in the reproductive system and the urinary tract.

Safed musli is highly recommended by specialists in the Ayurvedic medicine because it seems to have properties that improve semen count, semen volume and sperm motility. These are the main factors that affect the fertility in men. Safed musli is also helpful in a great variety of other conditions generated by a malfunctioning of the reproductive system. It seems to be increasing both fertility and performance in men.

Mucuna Pruriens (Kawach) is a medicinal plant, which has been mentioned in the treatises of ancient Indian texts such as the 'Charaka Samhita' and the 'Susrutha Samhita'. In Hindi, it is called 'Kawach'. Mucuna pruriens is the most powerful aphrodisiac. It also increases the testosterone level and the libido, by stimulating the production of dopamine. Mucuna pruriens also has effects at the level of the nervous system, toning it and increasing sensitivity and coordination.

Shilajit is an excellent restorative and rejuvenating tonic, it ensures good physical performance for the individual and leads to balanced and harmonious health. Shilajit is also known as sex tonic in India as it increases the core energy responsible for sexual drive or libido. It balances debility, general fatigue and provides strength to muscles and bones.

Aswagandha is another very effective herbal treatment for Azoospermia. This herb is renowned for providing anti-ageing effects and maintains secretion of human growth hormone. Regular intake of this herb keeps nerves relaxed and energized and also prevents occurrence of health disorders like anxiety, stress and depression, it also improves libido, controls blood sugar and maintains thyroid functions.

Satavari is another herbal treatment for Azoospermia which is used in various medicines and provides very effective natural cure to the problem. This herb rejuvenates reproductive organs and improves sperm quality naturally. This herb has been used to increase semen volume, sperm quantity and sperm motility since ancient times and is free of side effects.

Ayurvedic Panchkarma therapies :

A special panchkarma procedure known as Uttar basti is very helpful for this condition, Uttar basti should be given under the supervision of a trained ayurvedic doctor only.

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